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In the 3 sections below, learn about
the connection between DVT and PE,
understand the role of blood thinners,
and get information about ELIQUIS.
Did you know?
Patients who have had
a DVT or PE
are at risk for
EXPLORE MORE ABOUT DVT/PE BLOOD CLOTS BELOW
A DVT is a blood clot that
forms in a deep vein, usually
in the thighs or pelvis
The clot, or a part of the clot,
may break off and travel
through blood vessels toward
If that blood clot reaches the
lungs it is called a PE. A PE
can reduce or cut off blood
supply to the lungs, and may
even cause sudden death
If you have symptoms of DVT or PE, it is
important that you go to your doctor or to
the hospital right away. Don’t wait to see if
the symptoms will go away—waiting could
lead to serious complications. Keep in mind
that sometimes patients can have a DVT
and/or PE and not show any symptoms at all.
WHO IS AT RISK FOR HAVING ANOTHER DVT/PE?
If you’ve had deep vein thrombosis (DVT) or pulmonary embolism (PE), you may be at risk of having another case of DVT or PE. That’s known as a “recurrence.” Each patient's risk of recurrence varies.
It’s estimated that
1 out of 3 patients (33%) with DVT/PE
have a recurrence within 10 years.
The risk of recurrence is highest within
the first year after the initial DVT/PE.
In some cases, the risk of recurrence can
remain years after the first event.
Watch Ed share
share his reaction
to finding out he had DVT
and PE blood clots.
Ed was compensated for
his time and expenses.
You may ask
Do blood thinners increase the risk of bleeding?
Explore more about Blood thinners below
THEY TREAT DVT/PE BY
Reducing the ability of the
blood to clot
Reducing the risk of further
TREATMENT CAN HELP REDUCE THE RISK OF RECURRENCE
Taking certain blood thinners can help reduce the risk of recurrence. And that is why, after at least 6 months of a prescription treatment for DVT/PE, your doctor may ask you to continue on
ELIQUIS—a blood thinner that is clinically proven to reduce the risk of recurrence of DVT/PE after initial treatment for DVT/PE.
Blood thinners reduce the risk of “bad” blood clots that can form in a deep vein (usually in the
thighs or pelvis) and then break off and travel to the lungs.
Blood thinners can also slow the formation of “good” blood clots, causing unexpected bleeding or
preventing clots that form at the site of an injury to stop the bleeding.
Because they help reduce the risk of blood clots forming, blood thinners increase
the risk of bleeding, which can be serious and rarely may lead to death.
While taking a blood thinner, you may bruise more easily and it may take longer
than usual for any bleeding to stop. Be sure to seek medical
attention right away if you
or symptoms of bleeding such as unexpected bleeding or bleeding that
lasts a long time. You may have a higher risk of bleeding if you take blood thinners and
take other medicines that increase your risk of bleeding.
Click here for more comprehensive information you should be aware of
about bleeding and ELIQUIS. Be sure to call your doctor or healthcare provider
right away if you fall or injure yourself, especially if you hit your head. Your doctor
or healthcare provider may need to examine you.
Take extra care using knives, scissors,
and nail clippers
Use an electric razor
Wear shoes or non-skid slippers
in the house
Use a soft toothbrush and waxed
Wear gloves when using sharp tools
or doing yard work
Watch Thomas tell how he and
he and his doctor discussed
of taking a blood thinner
when he was
ELIQUIS for DVT.
Thomas was compensated
for his time and expenses.
Find out how
ELIQUIS treats DVT/PE blood clots and reduces
the risk of them happening again
Explore more about Eliquis below
WHAT IS ELIQUIS?
ELIQUIS is a prescription medicine used to treat blood clots in the veins of your legs (deep vein
thrombosis) or lungs (pulmonary embolism), and reduce the risk of them occurring again. Only
you and your doctor can decide if ELIQUIS is right for you. ELIQUIS and other blood thinners
increase the risk of bleeding, which can be serious, and rarely may lead to death.
to treat DVT/PE blood
the risk of them
In clinical trials for patients
with DVT/PE, ELIQUIS:
Treated DVT/PE blood clots and had less major bleeding in a 6-month study vs. LOVENOX® (enoxaparin) followed by warfarin.
Helped prevent another DVT/PE in a separate 12-month study vs. placebo.
ELIQUIS and other blood thinners
increase the risk of bleeding, which can
be serious, and
rarely may lead to death.
In the 6-month study vs. LOVENOX® followed by warfarin:
Almost 98% of patients on ELIQUIS didn’t experience another DVT/PE blood clot.
If you're taking warfarin, consider talking to your doctor about ELIQUIS for both these reasons:
ELIQUIS was proven effective to
treat deep vein thrombosis (DVT) and
pulmonary embolism (PE) blood clots. Plus,
ELIQUIS had significantly less major bleeding*
than the standard of care, LOVENOX®
followed by warfarin.
*Major bleeding included noticeable bleeding with at least
1 of the following—a transfusion of 2 or more units of
blood; bleeding that
occurred in the brain, spine, eye, inside
the abdomen, around the heart, in a joint, or in a muscle,
leading to damage; or fatal bleeding.
What are the possible serious side effects of ELIQUIS? This is a list of some of the serious side effects of ELIQUIS.
ELIQUIS can cause bleeding, which can be serious, and rarely may lead to death. This is because ELIQUIS is a blood thinner medicine that reduces blood clotting. While taking ELIQUIS, you may bruise more easily and it may take longer than usual for any bleeding to stop.
You may have a higher risk of bleeding if you take ELIQUIS with other medicines that increase your risk of bleeding, such as:
Call your doctor or get medical help right away if you have any of these signs or symptoms of bleeding when taking ELIQUIS:
Spinal or epidural blood clots (hematoma)
People who take ELIQUIS, and have
medicine injected into their spinal or
epidural area, or have a spinal puncture,
have a risk of forming a blood clot that can cause long-term or permanent loss of the ability to move (paralysis).
Your risk of developing a spinal or epidural blood clot is higher if:
If you take ELIQUIS and receive spinal anesthesia or have a spinal puncture, your doctor should watch you closely for symptoms of spinal or epidural blood clots or bleeding.
Tell your doctor right away if you have any of these signs or symptoms (especially in your legs and feet) when taking ELIQUIS:
A reaction to ELIQUIS itself
A reaction to ELIQUIS can cause hives, rash, itching, and possibly trouble breathing. If you get this reaction, it will usually happen soon after you take a dose of ELIQUIS.
Get medical help right away if you have any of the following symptoms:
Talk to your doctor about any side effect that may be bothering you or that does not go away. These are not all of the possible side effects of ELIQUIS. Call your doctor for medical advice about side effects.
You are encouraged to report any side effects to the FDA at 1-800-FDA-1088.
Who should not take ELIQUIS?
ELIQUIS is not for patients who:
What should I discuss with my healthcare team before starting ELIQUIS?
Talk to your healthcare team about the following:
Tell your doctor if you are pregnant or breastfeeding, or planning to become pregnant or breastfeed. You and your doctor should decide if you will take ELIQUIS or breastfeed. You should not do both.
Females who are able to become pregnant: talk with your healthcare provider about pregnancy planning, and your risk of severe uterine bleeding if you are treated with blood thinner medicines, including ELIQUIS.
Tell your healthcare team about all the medicines you take, including any:
How should I take ELIQUIS?
Take ELIQUIS exactly as prescribed by your doctor.
With or without food
Do not change your dose or stop taking ELIQUIS unless your doctor tells you to.
What if I miss a dose of ELIQUIS?
If you miss a dose of ELIQUIS, take it as soon as you remember, and do not take more than one dose at the same time.
When should I refill my prescription?
If you are taking ELIQUIS for atrial fibrillation, stopping ELIQUIS may increase your risk of having a stroke. Do not
run out of ELIQUIS. Refill your prescription before
you run out. When leaving the hospital following hip or knee replacement, be sure that
you will have ELIQUIS available to avoid missing any doses.
ELIQUIS is available in two different tablets. Your doctor or healthcare provider will determine what dose is right for you.
2.5 mg tablet
Round, with a pale yellow color
5 mg tablet
Oval, with a pale orange or pink color
Note: Images do not represent actual tablet size.
On one side of each tablet, there is a number indicating the dosage
strength of the tablet (in milligrams).
On the other side, there is a
medication identification number.
What is ELIQUIS?
ELIQUIS is a prescription medicine used to:
Reduce the risk of stroke and
blood clots in people who have
atrial fibrillation (AFib),
a type of irregular heartbeat,
caused by a heart valve
Treat blood clots in the
veins of the legs (deep vein thrombosis – DVT) or lungs
(pulmonary embolism – PE), and
reduce the risk of them occurring again.
Reduce the risk of forming a
blood clot in the legs (DVT)
and lungs (PE) of people who
have just had hip or knee replacement surgery.
LOVENOX® is a registered trademark of Aventis Pharma S.A.
The product information provided in this
site is intended only for residents of the
United States. The products discussed herein may have different product labeling in
The health information contained herein is provided for educational purposes only and is not intended to replace discussions with
a healthcare provider. All decisions
regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient.
You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
For people taking ELIQUIS® (apixaban) for atrial fibrillation: Do not stop taking ELIQUIS without talking to the doctor who
prescribed it for you. Stopping ELIQUIS increases your risk of having a stroke.
ELIQUIS may need to be stopped prior to surgery or a medical or dental procedure. Your doctor will tell you when you should stop
taking ELIQUIS and when you may start taking it again. If you have to stop taking ELIQUIS, your doctor may prescribe another
medicine to help prevent a blood clot from forming.
ELIQUIS can cause bleeding, which can be serious, and rarely may lead to death. This is because ELIQUIS is a blood thinner
medicine that reduces blood clotting.
You may have a higher risk of bleeding if you take ELIQUIS and take other medicines that increase your risk of bleeding, such as
aspirin, nonsteroidal anti-inflammatory drugs (called NSAIDs), warfarin (COUMADIN®), heparin, selective serotonin reuptake
inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs), and other medicines to help prevent or treat blood clots.
Tell your doctor about all of the medicines you take, including any over-the-counter medicines, vitamins, and herbal supplements.