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INDICATIONS
In the 3 sections below, learn about the connection
between DVT and PE, understand the role of blood thinners,
and get information about ELIQUIS.
He was compensated for his
time and expenses.
He was compensated for his
time and expenses.
If you’ve had a DVT or PE, you may
be at risk for having another
EXPLORE MORE ABOUT DVT/PE BLOOD CLOTS BELOW
Deep vein thrombosis (DVT)
&
pulmonary embolism (PE)
are serious conditions
A DVT is a blood clot that forms in a deep vein, usually in the thighs or pelvis
The clot, or a part of the clot, may break off and travel through blood vessels toward the lungs
If that blood clot reaches the lungs it is called a PE. A PE can reduce or cut off blood supply to the lungs, and may even cause sudden death
Swelling in the leg or
around a vein in the leg
Pain or tenderness felt when standing
or walking
Redness around the
affected area
Difficulty breathing
Faster than normal or irregular heartbeat
Chest pain
Coughing up blood
Very low blood pressure,
light-headedness, or fainting
If you have symptoms of DVT or PE, it is important that you go to your doctor or to the hospital right away. Don’t wait to see if the symptoms will go away—waiting could lead to serious complications.
Keep in mind that sometimes people can have a DVT and/or PE and not show any symptoms at all.
Who Is at Risk for Having
Another DVT/PE?
If you’ve had deep vein thrombosis (DVT)
or pulmonary embolism (PE),
you may
be at risk of having another case of DVT
or PE. That’s known
as a “recurrence.”
Each person’s risk of recurrence varies.
How Common Is Recurrence?
It’s estimated that
1 out of 3 people (33%) with DVT/PE
have a recurrence within 10 years
Other important things to keep in mind:
The risk of recurrence is highest within
the first year after the initial DVT/PE
In some cases, the risk of recurrence can
remain years after the first event
Do blood thinners increase
the risk of bleeding?
EXPLORE MORE ABOUT BLOOD THINNERS BELOW
Blood thinners are the
most common treatment for DVT/PE
THEY TREAT DVT/PE BY
Reducing the
ability of the
blood to clot
Reducing the
risk
of further
clots
developing
Treatment can help reduce
the risk of recurrence
Taking certain blood thinners can help reduce the risk of recurrence. And that is why,
after at least 6 months of a prescription treatment for DVT/PE, your doctor may ask you
to continue on ELIQUIS—a blood thinner that is clinically proven to reduce the risk of
recurrence of DVT/PE after initial treatment for DVT/PE.
Blood thinners reduce the risk of “bad”
blood clots that can form in a deep vein
(usually in the thighs or pelvis)
and then break off and travel to the lungs.
Blood thinners can also slow
the formation
of “good” blood clots, causing unexpected
bleeding or preventing clots that form at
the site of an injury to stop the bleeding.
Because they help reduce the
risk of blood clots forming,
blood thinners increase the risk of bleeding,
which can be serious and rarely may lead to death.
While taking a blood thinner, you may
bruise more easily and it may
take longer
than usual for any bleeding to stop.
Be sure to seek medical attention right away if you have signs or symptoms of bleeding such as unexpected bleeding or bleeding that lasts a long time. You may have a higher risk of bleeding if you take blood thinners and take other medicines that increase your risk of bleeding.
Click here for more comprehensive information you should be aware of about bleeding and ELIQUIS.
Your doctor may encourage you to limit
activities that may
cause injury and take
some precautions, such as:
Take extra care using knives,
scissors, and nail clippers
Use a soft toothbrush and
waxed dental floss
Use an electric razor
Wear gloves when using sharp
tools or doing yard work
Wear shoes or non-skid
slippers in the house
Take extra care using knives,
scissors, and nail clippers
Use an electric razor
Wear shoes or non-skid
slippers in the house
Use a soft toothbrush and
waxed dental floss
Wear gloves when using sharp
tools or doing yard work
ELIQUIS treats DVT/PE blood clots and reduces the risk of them
happening again
EXPLORE MORE ABOUT ELIQUIS BELOW
What Is ELIQUIS?
ELIQUIS is a prescription medicine used to
treat blood clots in the veins of your legs
(deep vein thrombosis) or lungs (pulmonary embolism), and reduce the risk of them
occurring again. Only you and your doctor can decide if ELIQUIS is right for you.
ELIQUIS was proven to
treat and
help prevent
another DVT or
PE blood clot
Almost 98 percent
of patients
on
ELIQUIS®
(apixaban)
didn’t experience
another
ELIQUIS has both
For patients with
DVT/PE, ELIQUIS:
Treats and helps
prevent another DVT/PE
Has significantly less major
bleeding than warfarin
Treated DVT/PE blood clots and had less major
bleeding in a
6-month study vs. LOVENOX®
(enoxaparin) followed by warfarin.
Helped prevent another DVT/PE in a separate
12-month study vs. placebo.
ELIQUIS and other blood thinners increase
the risk of bleeding,
which can be serious,
and rarely may lead to death.
In the 6-month study vs. LOVENOX®
followed by warfarin:
Almost 98% of patients on ELIQUIS didn’t
experience another DVT/PE blood clot.
Major bleeding included noticeable bleeding with
at least 1 of the following—a transfusion of 2 or more
units of blood; bleeding that occurred in the brain,
spine, eye, inside the abdomen, around the heart, in a joint,
or in a muscle, leading to damage; or fatal bleeding.
Do not stop taking ELIQUIS without talking to the doctor who prescribed it to you
For patients taking ELIQUIS for atrial fibrillation: stopping ELIQUIS increases your risk of having a stroke.
Talk to your healthcare team before any medical procedures. ELIQUIS may need to be stopped before surgery, or a medical or dental procedure. Your doctor will tell you when you should stop taking ELIQUIS and when you may start taking it again. If you have to stop taking ELIQUIS your doctor may prescribe another medicine to help prevent a blood clot from forming.
What are the possible serious side effects of ELIQUIS?
This is a list of some of the serious side effects of ELIQUIS.
Bleeding
ELIQUIS can cause bleeding, which can be serious, and rarely may lead to death. This is because ELIQUIS is a blood thinner medicine that reduces blood clotting. While taking ELIQUIS, you may bruise more easily and it may take longer than usual for any bleeding to stop.
You may have a higher risk of bleeding if you take ELIQUIS with other medicines that increase your risk of bleeding, such as:
Tell your doctor if you take any of these medicines.
Call your doctor or get medical help right away if you have any of these signs or symptoms of bleeding when taking ELIQUIS:
People who take ELIQUIS, and have medicine injected into their spinal or epidural area, or have a spinal puncture, have a risk of forming a blood clot that can cause long-term or permanent loss of the ability to move (paralysis).
Your risk of developing a spinal or epidural blood clot is higher if:
If you take ELIQUIS and receive spinal anesthesia or a spinal puncture, your doctor should watch you closely for symptoms of spinal or epidural blood clots
or bleeding.
Tell your doctor right away if you have any of these signs or symptoms (especially in your legs and feet) when taking ELIQUIS:
A reaction to ELIQUIS itself
A reaction to ELIQUIS can cause hives, rash, itching, and possibly trouble breathing. If you get this reaction, it will usually happen soon after you take a dose of ELIQUIS.
Get medical help right away if you have any of the following symptoms:
Talk to your doctor about any side effect that may be bothering you or that does not go away. These are not all of the possible side effects of ELIQUIS. Call your doctor for medical advice about side effects.
You are encouraged to report any side effects to the FDA at 1-800-FDA-1088.
Who should not take ELIQUIS?
ELIQUIS is not for patients who:
What should I discuss with my healthcare team before starting ELIQUIS?
Talk to your healthcare team about the following:
Tell your doctor if you are pregnant or breastfeeding, or planning to become pregnant or breastfeed. You and your doctor should decide if you will take ELIQUIS or breastfeed. You should not do both.
Tell your healthcare team about all of the medications you are taking, including:
During treatment, make sure you talk to your healthcare team before you begin to take any new medication.
How should I take ELIQUIS?
Take ELIQUIS exactly as prescribed by your doctor.
Do not change your dose or stop taking ELIQUIS unless your doctor tells you to.
What if I miss a dose of ELIQUIS?
If you miss a dose of ELIQUIS, take it as soon as you remember, and do not take more than one dose at the same time.
When should I refill my prescription?
If you are taking ELIQUIS for atrial fibrillation, stopping ELIQUIS may increase your risk of having a stroke. Do not run out of ELIQUIS. Refill your prescription before you run out. When leaving the hospital following hip or knee replacement, be sure that you will have ELIQUIS available to avoid missing any doses.
ELIQUIS is available in two different tablets. Your doctor or healthcare provider will determine what dose is right for you.
2.5 mg tablet
Round, with a pale yellow color
5 mg tablet
Oval, with a pale orange or pink color
Note: Images do not represent actual tablet size.
On one side of each tablet, there is a number indicating the dosage strength of the tablet (in milligrams). On the other side, there is a medication identification number.
What is ELIQUIS?
ELIQUIS is a prescription medicine used to:
Reduce the risk of stroke and blood clots in people who have atrial fibrillation (AFib),
a type of irregular heartbeat, not
caused by a heart valve problem.
Treat blood clots in the veins of the legs (deep vein thrombosis – DVT) or lungs
(pulmonary embolism – PE), and reduce
the risk of them occurring again.
Reduce the risk of forming a blood clot in the legs (DVT) and lungs (PE) of people
who have just had hip or knee replacement surgery.
Please see U.S. Full Prescribing Information, including Boxed WARNINGS and Medication Guide.
LOVENOX® is a registered trademark of Aventis Pharma S.A.
The product information provided in this site is intended only for residents of the United States. The products discussed herein may have different product labeling in different countries.
The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call
432US1802406-03-01 07/19
For people taking ELIQUIS® (apixaban) for atrial fibrillation: Do not stop taking ELIQUIS without talking to the doctor who prescribed it for you. Stopping ELIQUIS increases your risk of having a stroke.
ELIQUIS may need to be stopped prior to surgery or a medical or dental procedure. Your doctor will tell you when you should stop taking ELIQUIS and when you may start taking it again. If you have to stop taking ELIQUIS, your doctor may prescribe another medicine to help prevent a blood clot from forming.
ELIQUIS can cause bleeding, which can be serious, and rarely may lead to death. This is because ELIQUIS is a blood thinner medicine that reduces blood clotting.
You may have a higher risk of bleeding if you take ELIQUIS and take other medicines that increase your risk of bleeding, such as aspirin, nonsteroidal anti-inflammatory drugs (called NSAIDs), warfarin (COUMADIN®), heparin, selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs), and other medicines to help prevent or treat blood clots. Tell your doctor about all of the medicines you take, including any over-the-counter medicines, vitamins, and herbal supplements.
ELIQUIS® and the ELIQUIS logo are trademarks of Bristol-Myers Squibb Company.
COUMADIN® is a registered trademark of Bristol-Myers Squibb Pharma Company.
All other trademarks are property of their
respective companies.
© 2020 Bristol-Myers Squibb Company. 432US1904257-01-01 01/20
Please see U.S. Full Prescribing Information including Boxed WARNINGS and Medication Guide.
For people taking ELIQUIS® (apixaban) for atrial fibrillation: Do not stop taking ELIQUIS without talking to the doctor who prescribed it for you. Stopping ELIQUIS increases your risk of having a stroke.
ELIQUIS may need to be stopped prior to surgery or a medical or dental procedure. Your doctor will tell you when you should stop taking ELIQUIS and when you may start taking it again. If you have to stop taking ELIQUIS, your doctor may prescribe another medicine to help prevent a blood clot from forming.
ELIQUIS can cause bleeding, which can be serious, and rarely may lead to death. This is because ELIQUIS is a blood thinner medicine that reduces blood clotting.
You may have a higher risk of bleeding if you take ELIQUIS and take other medicines that increase your risk of bleeding, such as aspirin, nonsteroidal anti-inflammatory drugs (called NSAIDs), warfarin (COUMADIN®), heparin, selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs), and other medicines to help prevent or treat blood clots. Tell your doctor about all of the medicines you take, including any over-the-counter medicines, vitamins, and herbal supplements.
While taking ELIQUIS, you may bruise more easily and it may take longer than usual for any bleeding to stop.
Call your doctor or get medical help right away if you have any of these signs or symptoms of bleeding when taking ELIQUIS:
ELIQUIS (apixaban) is not for patients with artificial heart valves.
Spinal or epidural blood clots (hematoma). People who take ELIQUIS, and have medicine injected into their spinal and epidural area, or have a spinal puncture have a risk of forming a blood clot that can cause long-term or permanent loss of the ability to move (paralysis). Your risk of developing a spinal or epidural blood clot is higher if:
If you take ELIQUIS and receive spinal anesthesia or have a spinal puncture, your doctor should watch you closely for symptoms of spinal or epidural blood clots or bleeding. Tell your doctor right away if you have tingling, numbness, or muscle weakness, especially in your legs and feet.
ELIQUIS is not for use in people with antiphospholipid syndrome (APS), especially with positive triple antibody testing, who have a history of blood clots.
Do not take ELIQUIS if you currently have certain types of abnormal bleeding or have had a serious allergic reaction to ELIQUIS.
Before you take ELIQUIS, tell your doctor if you have kidney or liver problems, have antiphospholipid syndrome, have any other medical condition, or have ever had bleeding problems. Tell your doctor if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. You and your doctor should decide if you will take ELIQUIS or breastfeed. You should not do both.
Take ELIQUIS exactly as prescribed by your doctor. Take ELIQUIS twice every day with or without food, and do not change your dose or stop taking it unless your doctor tells you to. If you miss a dose of ELIQUIS, take it as soon as you remember, and do not take more than one dose at the same time. If you are taking ELIQUIS for atrial fibrillation, stopping ELIQUIS may increase your risk of having a stroke. Do not run out of ELIQUIS. Refill your prescription before you run out. When leaving the hospital following hip or knee replacement, be sure that you will have ELIQUIS available to avoid missing any doses.
Possible serious side effects include bleeding or a reaction to ELIQUIS itself. A reaction to ELIQUIS can cause hives, rash, itching, and possibly trouble breathing. If you get this reaction, it will usually happen soon after you take a dose of ELIQUIS. Get medical help right away if you have sudden chest pain or chest tightness, have sudden swelling of your face or tongue, have trouble breathing, wheezing, or feeling dizzy or faint.
ELIQUIS (apixaban) is a prescription medicine used to reduce the risk of stroke and blood clots in people who have atrial fibrillation, a type of irregular heartbeat, not caused by a heart valve problem.
ELIQUIS is a prescription medicine used to treat blood clots in the veins of your legs (deep vein thrombosis) or lungs (pulmonary embolism), and reduce the risk of them occurring again.
ELIQUIS is a prescription medicine used to reduce the risk of forming a blood clot in the legs and lungs of people who have just had hip or knee replacement surgery.
Please see U.S. Full Prescribing Information, including Boxed WARNINGS and Medication Guide.
ELIQUIS is available in 2.5-mg and 5-mg tablets.
COUMADIN® is a registered trademark of Bristol-Myers Squibb Pharma Company. All other trademarks are property of their respective companies.
LOVENOX® is a registered trademark of Aventis Pharma S.A.
This independent, non-profit organization provides assistance to qualifying patients with financial hardship who generally have no prescription insurance. Contact 1-800-736-0003 or visit www.bmspaf.org for more information.
The product information provided in this site is intended only for residents of the United States. The products discussed herein may have different product labeling in different countries.
The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.