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Do not stop taking ELIQUIS without talking to the doctor who prescribed it to you.

For patients taking ELIQUIS for atrial fibrillation: stopping ELIQUIS increases your risk of having a stroke.
Talk to your healthcare team before any surgery, medical, or dental procedures. Learn more below.



ELIQUIS can cause bleeding, which can be serious, and rarely may lead to death. This is because ELIQUIS is a blood thinner medicine that reduces blood clotting. While taking ELIQUIS, you may bruise more easily and it may take longer than usual for any bleeding to stop. Be sure to seek medical attention right away if you have signs or symptoms of bleeding, such as unexpected bleeding or bleeding that lasts a long time. You may have a higher risk of bleeding if you take blood thinners and take other medicines that increase your risk of bleeding. See below for more comprehensive information you should be aware of about bleeding and ELIQUIS.


Spinal or epidural blood clots (hematoma)

People who take ELIQUIS, and have medicine injected into their spinal or epidural area, or have a spinal puncture, have a risk of forming a blood clot that can cause long-term or permanent loss of the ability to move (paralysis). Learn more about the risk of developing an epidural blood clot while taking ELIQUIS.


A reaction to ELIQUIS itself

A reaction to ELIQUIS can cause hives, rash, itching, and possibly trouble breathing. If you get this reaction, it will usually happen soon after you take a dose of ELIQUIS. Get medical help right away if you have sudden chest pain or chest tightness, have sudden swelling of your face or tongue, have trouble breathing, wheezing, or feeling dizzy or faint. See more about possible serious side effects.


These are not all of the possible side effects of ELIQUIS. Call your doctor for medical advice about side effects.

See below for more important safety information about ELIQUIS.


Talking With Your Doctor

Get tips from a nurse for talking with a doctor and download a discussion guide to help you make the most of your time with your healthcare professional.



About DVT/PE

Learn how a deep vein thrombosis (DVT) blood clot can lead to a pulmonary embolism (PE), and the role of ELIQUIS to treat DVT/PE and reduce the risk of them happening again.




Find out more about ELIQUIS, including clinical study results, possible side effects, and additional factors for you and your healthcare professional to consider.