Indications
-
ELIQUIS (apixaban) is a prescription
medicine used in adults to reduce the risk of stroke and blood clots in people who have atrial fibrillation (AFib), a type of irregular heartbeat, not caused by a heart valve problem.
-
ELIQUIS (apixaban) is a prescription
medicine used in adults to treat blood clots in the veins of your legs (deep vein thrombosis-DVT) or lungs (pulmonary embolism-PE), and to reduce the risk of them occurring again after receiving treatment for blood clots. -
ELIQUIS (apixaban) is a prescription
medicine used in children from birth and older to treat blood clots in the veins of legs and lungs (venous thromboembolism) after at least 5 days of initial anticoagulant treatment, and to reduce the risk of them happening again. ELIQUIS was not studied and is not recommended in children weighing less than 5.7 pounds (2.6 kg). -
ELIQUIS (apixaban) is a prescription
medicine used in adults to help prevent a blood clot in the veins of your legs (deep vein thrombosis-DVT) and lungs (pulmonary embolism-PE) of people who have just had hip or knee replacement surgery.
Indications
-
ELIQUIS (apixaban) is a
prescription medicine used in adults to reduce the risk of stroke and blood clots in people who have atrial fibrillation (AFib), a type of irregular heartbeat, not caused by a heart valve problem. -
ELIQUIS (apixaban) is a
prescription medicine used in adults to treat blood clots in the veins of your legs (deep vein thrombosis-DVT) or lungs (pulmonary embolism-PE), and to reduce the risk of them occurring again after receiving treatment for blood clots. -
ELIQUIS (apixaban) is
a prescription medicine used in children from birth and older to treat blood clots in the veins of legs and lungs (venous thromboembolism) after at least 5 days of initial anticoagulant treatment, and to reduce the risk of them happening again. ELIQUIS was not studied and is not recommended in children weighing less than 5.7 pounds (2.6 kg). -
ELIQUIS (apixaban) is a
prescription medicine used in adults to help prevent a blood clot in the veins of your legs (deep vein thrombosis-DVT) and lungs (pulmonary embolism-PE) of people who have just had hip or knee replacement surgery.
This page includes dosing instructions for adults taking oral ELIQUIS tablets. For dosing instructions for children who take ELIQUIS, please click here.
Take ELIQUIS exactly as prescribed
Take ELIQUIS twice every day. If you have difficulty swallowing the tablet whole, talk to your healthcare provider about other ways to take ELIQUIS. Do not change your dose or stop taking ELIQUIS unless your healthcare provider tells you to.
If you miss a dose
If you miss a dose of ELIQUIS, take it as soon as you remember on the same day. Do not take 2 doses of ELIQUIS at the same time to make up for a missed dose. Return to your usual dosing schedule the next day.
Keep your prescription filled
Do not run out of ELIQUIS. Refill your prescription before you run out. Your healthcare provider will decide how long you should take ELIQUIS. Don’t change your dose or stop taking ELIQUIS unless your healthcare provider tells you to. If you stop taking ELIQUIS, you may have increased risk of forming a clot in your blood.
If you take too much ELIQUIS, call your healthcare provider or go to the nearest hospital emergency room right away.
Call your healthcare provider right away if you fall or injure yourself, especially if you hit your head. Your healthcare provider may need to check you.
To learn more, see What you should know before taking ELIQUIS.
Symptoms of bleeding
ELIQUIS can cause bleeding, which can be serious, and may lead to death. This is because ELIQUIS is a blood thinner medicine that reduces blood clotting.
CALL YOUR HEALTHCARE PROVIDER OR GET MEDICAL HELP RIGHT AWAY IF YOU HAVE ANY OF THESE SIGNS OR SYMPTOMS OF BLEEDING WHEN TAKING ELIQUIS:
- Unexpected bleeding or bruising, or bleeding that lasts a long time, such as unusual bleeding from the gums, nose bleeds that happen often, or menstrual or vaginal bleeding that is heavier than normal
- Bleeding that is severe or you cannot control
- Red, pink, or brown urine; red or black stools (looks like tar)
- Coughing up or vomiting blood, or vomit that looks like "coffee grounds"
- Unexpected pain, swelling, or joint pain
- Headaches, or feeling dizzy or weak
While taking ELIQUIS, you may bruise more easily and it may take longer than usual for any bleeding to stop.
Your ELIQUIS dosage
If you’re an adult taking ELIQUIS following an initial 6 months of DVT/PE treatment to reduce the risk of recurrence, your dosage will be different. Your healthcare provider will determine what dose is right for you. You can learn about this dosage by clicking the “Download Now” button below.
For either dose, make sure you follow your healthcare provider's instructions when taking ELIQUIS.
For information about dosing for children who take ELIQUIS, click here to learn more.
Treating DVT/PE
First 7 days
Two 5-mg tablets twice a day
After 7 days
One 5-mg tablet twice a day
Reducing risk of recurrent DVT/PE after initial therapy
After at least 6 months
of DVT/PE treatment
One 2.5-mg tablet twice a day
The ELIQUIS Dosing Guide for Adults
Download the Dosing Guide with a calendar to help you keep track of your ELIQUIS dosage during the first 2 weeks of treatment.
The way I remember to take ELIQUIS twice a day is to just do it when I brush my teeth, morning and night.
Brian is a paid patient ambassador.
I set an alarm on my phone to remember to take ELIQUIS twice a day, every morning and evening.
LaVon is a paid patient ambassador.
Having a hard time remembering to take your medication?
These simple suggestions may help.
Set alarms or alerts
Use your watch or your smartphone.
Create a pill reminder card
Post it on your fridge or somewhere you’ll see each day and consider using a pill organizer.
Time around daily activity
Time your medication to a daily activity, like brushing your teeth.
Keep your meds in sight
Consider places like your kitchen counter or bedroom dresser (but always keep medications away from children).
Make it a habit
Take your medication at the same time each morning and evening.
What you should know before taking ELIQUIS
ELIQUIS is not for patients who:
- have artificial heart valves
- have antiphospholipid syndrome (APS), especially with positive triple antibody testing.
- currently have certain types of abnormal bleeding
- have had a serious allergic reaction to ELIQUIS or any of the ingredients
See additional Important Safety Information below.
Talk to your healthcare team if you:
- Have or ever had bleeding problems
- Have kidney or liver problems
- Have antiphospholipid syndrome (APS)
- Are pregnant or plan to become pregnant. It is not known if ELIQUIS will harm your unborn baby
Tell your healthcare provider right away if you become pregnant during treatment with ELIQUIS. Taking ELIQUIS during pregnancy may increase the risk of bleeding in you or your unborn baby.
Females who are able to become pregnant: talk with your healthcare provider about pregnancy planning, and your risk of severe uterine bleeding if you are treated with ELIQUIS.
Tell your healthcare provider if you are breastfeeding or plan to breastfeed. It is not known if ELIQUIS passes into your breast milk. Do not breastfeed during treatment with ELIQUIS. Talk to your healthcare provider about the best way to feed your baby during treatment with ELIQUIS.
Tell your healthcare team about all the medicines you take, including any:
- prescription medicines
- over-the-counter medicines
- vitamins
- Herbal supplements
During treatment, make sure you talk to your healthcare team before you begin to take any new medication.
See additional Important Safety Information below.
Increased risk of blood clots if you stop taking ELIQUIS
ELIQUIS lowers your chance of having a stroke by helping prevent clots from forming. If you stop taking ELIQUIS, you may have an increased risk of a clot forming in your blood.
Do not stop taking ELIQUIS without talking to the healthcare provider who prescribed it to you
Stopping ELIQUIS increases your risk of having a stroke.
Talk to your healthcare team before any medical procedures. ELIQUIS may need to be stopped before surgery or a medical or dental procedure. Your healthcare will tell you when you should stop taking ELIQUIS and when you may start taking it again. If you have to stop taking ELIQUIS, your health provider may prescribe another medicine to help prevent a blood clot from forming.
Bleeding
ELIQUIS can cause bleeding, which can be serious, and may lead to death. This is because ELIQUIS is a blood thinner medicine that reduces blood clotting. While taking ELIQUIS, you may bruise more easily and it may take longer than usual for any bleeding to stop.
You may have a higher risk of bleeding if you take ELIQUIS and other medicines that increase your risk of bleeding, such as:
- Aspirin or aspirin-containing products
- Long-term (chronic) nonsteroidal anti-inflammatory drugs (called NSAIDs)
- Warfarin sodium
- Any medicine that contains heparin
- Clopidogrel
- Selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs)
- Other medicines to help prevent or treat blood clots
Tell your healthcare provider if you take any of these medicines.
Call your healthcare provider or get medical help right away if you have any of these signs or symptoms of bleeding when taking ELIQUIS:
- Unexpected bleeding or bruising, or bleeding that lasts a long time, such as:
- Unusual bleeding from the gums
- Nosebleeds that happen often
- Menstrual or vaginal bleeding that is heavier than normal
- Bleeding that is severe or you cannot control
- Red, pink, or brown urine
- Red or black stools (looks like tar)
- Coughing up or vomiting blood or blood clots
- Vomit that looks like coffee grounds
- Unexpected pain, swelling, or joint pain
- Headaches
- Feeling dizzy or weak
Spinal or epidural blood clots (hematoma)
People who take a blood thinner medicine like ELIQUIS, and have medicine injected into their spinal or epidural area, or have a spinal puncture, have a risk of forming a blood clot that can cause long-term or permanent loss of the ability to move (paralysis).
Your risk of developing a spinal or epidural blood clot is higher if:
- A thin tube called an epidural catheter is placed in your back to give you certain medicine
- You take NSAIDs or a medicine to prevent blood from clotting
- You have a history of difficult or repeated epidural or spinal punctures
- You have a history of problems with your spine or have had surgery on your spine
If you take ELIQUIS and receive spinal anesthesia or have a spinal puncture, your healthcare provider should watch you closely for symptoms of spinal or epidural blood clots or bleeding.
Tell your healthcare provider right away if you have any of these signs or symptoms when taking ELIQUIS:
- Back pain
- Tingling, numbness, or muscle weakness, especially in your legs and feet
- Loss of control of the bowels or bladder (incontinence)
Talk to your healthcare provider about any side effect that may be bothering you or that does not go away. These are not all of the possible side effects of ELIQUIS. Call your healthcare provider for medical advice about side effects.
You are encouraged to report any side effects to the FDA at 1-800-FDA-1088.
These are not all of the possible side effects of ELIQUIS. For more information, ask your doctor or pharmacist.
See additional Important Safety Information below.
The ELIQUIS Starter Guide
Get going with helpful information about activating your Co-pay Card,† filling your prescription, and taking ELIQUIS.
†If eligible.
Talking With Your Doctor
Get tips from a nurse for talking with a doctor and download a discussion guide to help you make the most of your time with your healthcare professional.
ELIQUIS 360 Support
Connect with ELIQUIS 360 Support for prescription coverage assistance and to sign up to receive helpful information about your condition and taking ELIQUIS.
Savings Resources
Learn about the Free Trial Offer and how eligible patients can potentially save on out-of-pocket costs with the ELIQUIS Co-pay Card.